Yes, it is possible to wear the Valve Index with glasses. The headset has an adjustable eye relief mechanism that allows users to physically adjust the distance between the lenses and your eyes, which can help accommodate the use of glasses.
Additionally, the Valve Index has a wide variety of third party accessories that will improve comfort. The headset’s design by default allows for enough room between the lenses and the user’s face, which can prevent the glasses from getting scratched or damaged during use.
However, it is still important to ensure that the glasses fit comfortably and securely inside the headset to avoid discomfort or potential damage to the glasses. If you have particularly large or bulky glasses, you may want to consider trying the headset on in person or contacting the manufacturer to ensure that they are compatible with the Valve Index.